Sample Size -- Survival Outcomes  

Shih/SIZE

Non-proportional hazards case

Power

Ratio of sample size, control vs treated

Number equal length study periods

List control rates of event for each period

List hazard ratios, treated vs control, for each period

Type of patient entry  

Number study periods for uniform patient entry

Two-sided Type I error

Test statistic

Periods to achieve full treatment effect

List loss to follow-up rates for each period

List rates of crossover to treated for each period

Lag in effect of crossover to treated

List rates of crossover to control for each period